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Index > Protein center > Tmpo(Gene name) > Mouse
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  • Tmpo (Gene name),
  • Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma (Protein name ),  LAP2B_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Tmpo(Lap2);
    Protein name:
    Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma;
    Alternative:
    Thymopoietin isoforms beta/delta/epsilon/gamma(TP beta/delta/epsilon/gamma);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with LMNB1, LMNB2, BANF1, AKAP8L, GMCL and chromosomes.
    Function:
    May help direct the assembly of the nuclear lamina and thereby help maintain the structural organization of the nuclear envelope. Possible receptor for attachment of lamin filaments to the inner nuclear membrane. May be involved in the control of initiation of DNA replication through its interaction with NAKAP95.
    Subcellular Location:
    Nucleus inner membrane Single-pass type II membrane protein Chromosome Tightly associated with the nuclear lamina.
    Protein Attributes:
    Sequence length:
    452
    Sequence:
    50:
    MPEFLEDPSV | LTKDKLKSEL | VANNVTLPAG | EQRKDVYVQL | YLQHLTARNR | 
    100:
    PPLAAGANSK | GPPDFSSDEE | REPTPVLGSG | ASVGRGRGAV | GRKATKKTDK | 
    150:
    PRLEDKDDLD | VTELSNEELL | DQLVRYGVNP | GPIVGTTRKL | YEKKLLKLRE | 
    200:
    QGTESRSSTP | LPTVSSSAEN | TRQNGSNDSD | RYSDNDEDSK | IELKLEKREP | 
    250:
    LKGRAKTPVT | LKQRRTEHNQ | SYSQAGVTET | EWTSGSSTGG | PLQALTREST | 
    300:
    RGSRRTPRKR | VETSQHFRID | GAVISESTPI | AETIKASSNE | SLVANRLTGN | 
    350:
    FKHASSILPI | TEFSDITRRT | PKKPLTRAEV | GEKTEERRVD | RDILKEMFPY | 
    400:
    EASTPTGISA | SCRRPIKGAA | GRPLELSDFR | MEESFSSKYV | PKYAPLADVK | 
    450:
    SEKTKKRRSV | PMWIKMLLFA | LVAVFLFLVY | QAMETNQGNP | FTNFLQDTKI | 
    452:
    SN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    KEGG:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    MSDS:
    Please sign in first.
    ELISA Kit for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Cat.:
    E1250h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Cat.:
    E1250m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Cat.:
    U1250r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Cat.:
    U1250h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Cat.:
    U1250m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Cat.:
    P1250Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Cat.:
    P1250Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Cat.:
    P1250Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Monoclonal Antibody for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Monoclonal Antibody for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Protein for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Cat.:
    R1250h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
    Protein for Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The characterization and localization of the mouse thymopoietin/lamina-associated polypeptide 2 gene and its alternatively spliced products."
      Berger R. , Theodor L. , Shoham J. , Gokkel E. , Brok-Simoni F. , Avraham K.B. , Copeland N.G. , Jenkins N.A. , Rechavi G. , Simon A.J.
      Genome Res.6:361-370(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS ALPHA; BETA; GAMMA; DELTA; EPSILON AND ZETA)
      strain: C57BL/6 X DBA/2.
      tissue: Thymus.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Bone marrow.
      tissue: Lung.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "Identification of phosphorylation sites in native lamina-associated polypeptide 2 beta."
      Dreger M. , Otto H. , Neubauer G. , Mann M. , Hucho F.
      Biochemistry38:9426-9434(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 61-85 AND 173-194 (ISOFORM BETA);PHOSPHORYLATION AT THR-74; THR-159; SER-176 AND SER-179;IDENTIFICATION BY MASS SPECTROMETRY
    5. 5.
      "LAP2 binding protein 1 (L2BP1/BAF) is a candidate mediator of LAP2-chromatin interaction."
      Furukawa K.
      J. Cell Sci.112:2485-2492(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BANF1
    6. 6.
      "Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less)."
      Nili E. , Cojocaru G.S. , Kalma Y. , Ginsberg D. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Berger R. , Shaklai S. , Amariglio N. , Brok-Simoni F. , Simon A.J. , Rechavi G.
      J. Cell Sci.114:3297-3307(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GMCL
    7. 7.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-66; SER-67; THR-74 AND THR-159;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    9. 9.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
      Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-66; SER-67 AND THR-74;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CITRULLINATION AT ARG-319
    12. 12.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-206 AND LYS-388;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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